EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Children of Gaza caught in the crossfire

GAZA (Reuters) - Barefoot boys chase each other in circles around the street, pointing pretend guns made out of rubber pipes up at the Gaza sky, which is thick with Israeli F-16s and surveillance drones.

"We're not afraid of the Jews' bombs!" said Sharif al-Ewad, whose plump cheeks make him look younger than his 15 years. "Al-Qassam (Hamas's armed wing) has raised its head high, and is really beating them up this time!" he smiled.

But beneath the swagger and bravado there is also a yearning for peace and quiet after five days of Israeli airstrikes that killed at least 65 Palestinians, including 20 children.

With one of the youngest populations in the world, over half of Gaza's 1.7 million residents are aged under 18 and they have little to comfort them beside the heady local culture of armed struggle against Israel.

The Jewish state pulled its troops and settlers out of the coastal territory in 2005 but ever since has come under regular rocket fire from Islamist group Hamas and its allies in the Gaza Strip, which refuse to recognize Israel's right to exist.

Israel launched its latest widescale operation last Wednesday with the stated aim of putting a halt to the attacks.

Psychiatrist Hasan Zeyada says the constant exposure to shocking violence has left many children suffering trauma and all that it entails -- bed-wetting, nightmares, flashbacks, and fear of going out in public.

"Part of this is related to our culture and religion, which values sacrifice and duty. The other part is a kind of denial. it's normal to be scared, but in the messages they've watched and heard, they're taught just to show strength," said Zeyada, manager of the Gaza Community Mental Health Program.

"When there's no safe place to go, they respond naturally with denial. In a situation like Gaza's, the best families and the community can do for children is to keep them close and go about life as normally as possible," he said.

That isn't very easy.

SMALL VICTIMS

With schools shut while the fighting rages, some children express delight at their newfound freedom. "Of course we're happy!" squealed one boy, drawing out giggles from his mates.

Looking more serious, Sharif shook his head. "No, it's no good. We want to learn. It's boring, and our parents try to make us stay inside. But we're not scared," he insisted.

On the other side of the fence, Israeli schools are also shuttered within a 40-km radius of Gaza because of an incessant rain of incoming rockets, with children confined to their homes.

Tragically, some young Gazans will never get to see school.

Tamer, 1, and Joumana Abu Sefan, 3, were blasted from their beds by an Israeli strike early on Sunday. Their father Salama, blood gushing down his face from his owns wounds, rushed them to hospital, where they were pronounced dead.

Male relatives stared on in tears, women cried out and swooned while the little bodies were swaddled in white cloth and gauze was placed in their nostrils to keep still-flowing blood from staining their faces.

At their joint funeral march just hours later, Salama cradled their heads as uncles held them aloft at his side.

Green Hamas flags were suddenly draped over their shrouds, and the militant group's religious songs, playing in the background, announced that the tiny pair had achieved martyrdom and that heaven would be their reward.

"What does Israel want with their blood?" Salama heaved, inconsolable and seeming to sleepwalk through the spectacle.

For its part, Israel denies targeting civilians and says it is constantly warning residents, who it says are used by as human shields, away from areas where militants operate.

Abdullah Zumlot, 15, the first hints of moustache speckling his upper lip, scoffed at this as he loitered around the hospital where the Abu Sefan children were earlier carried away.

"It's not fair what we have to live through, we're not happy. All my family and I do is sit at home and watch the news 24 hours," he complained.

(Editing by Crispian Balmer)

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Obama: Historic Myanmar visit underscores progress

BANGKOK (AP) — On the eve of his landmark trip to Myanmar, President Barack Obama tried to assure critics that his visit was not a premature reward for a long-isolated nation still easing its way toward democracy.

"This is not an endorsement of the government," Obama said Sunday in Thailand as he opened a three-country dash through Asia. "This is an acknowledgement that there is a process under way inside that country that even a year and a half, two years ago, nobody foresaw."

Obama was set to become the first U.S. president to visit Myanmar with Air Force One scheduled to touch down in Yangon on Monday morning. Though Obama planned to spend just six hours in the country, the much-anticipated stop came as the result of a remarkable turnaround in the countries' relationship.

The president's Asia tour also marks his formal return to the world stage after months mired in a bruising re-election campaign. For his first postelection trip, he tellingly settled on Asia, a region he has deemed the region as crucial to U.S. prosperity and security.

Aides say Asia will factor heavily in Obama's second term as the U.S. seeks to expand its influence in an attempt to counter China.

China's rise is also at play in Myanmar, which long has aligned itself with Beijing. But some in Myanmar fear that China is taking advantage of its wealth of natural resources, so the country is looking for other partners to help build its nascent economy.

Obama has rewarded Myanmar's rapid adoption of democratic reforms by lifting some economic penalties. The president has appointed a permanent ambassador to the country, also known as Burma, and pledged greater investment if Myanmar continues to progress following a half-century of military rule.

But some human rights groups say Myanmar's government, which continues to hold hundreds of political prisoners and is struggling to contain ethnic violence, hasn't done enough to earn a personal visit from Obama.

Speaking from neighboring Thailand, Obama said Sunday he was under no illusions that Myanmar had done all it needed to do. But he said the U.S. could play a critical role in helping ensure the country doesn't slip backward.

"I'm not somebody who thinks that the United States should stand on the sidelines and not want to get its hands dirty when there's an opportunity for us to encourage the better impulses inside a country," Obama said during a joint press conference Sunday with Thailand's prime minister.

Even as Obama turned his sights on Asia, widening violence in the Middle East competed for his attention.

Obama told reporters Sunday that Israel had the right to defend itself against missile attacks from Gaza. But he urged Israel not to launch a ground assault in Gaza, saying it would put Israeli soldiers, as well as Palestinian citizens, at greater risk and hamper an already vexing peace process.

"If we see a further escalation of the situation in Gaza, the likelihood of us getting back on any kind of peace track that leads to a two-state solution is going to be pushed off way into the future," Obama said.

The ongoing violence is likely to trail Obama as he makes his way from Thailand to Myanmar to Cambodia, his final stop before returning to Washington early Wednesday.

Obama will meet separately in Myanmar with Prime Minister Thein Sein, who has orchestrated much of his country's recent reforms. The president will also meet with longtime Myanmar democracy activist Aung Sun Suu Kyi in the home where she spent years under house arrest.

The president, as he seeks to assuage critics, has trumpeted Suu Kyi's support of his outreach efforts, saying Sunday that she was "very encouraging" of his trip.

The White House says Obama will express his concern for the ongoing ethnic tensions in Myanmar's western Rakhine state, where more than 110,000 people — the vast majority of them Muslims known as Rohingya — have been displaced.

The U.N. has called the Rohingya — who are widely reviled by the Buddhist majority in Myanmar — among the world's most persecuted people.

The White House says Obama will press the matter Monday with Thein Sein, along with demands to free remaining political prisoners as the nation transitions to democracy.

The president will cap his trip to Myanmar with a speech at Rangoon University, the center of the country's struggle for independence against Britain and the launching point for many pro-democracy protests. The former military junta shut the dormitories in the 1990s fearing further unrest and forced most students to attend classes on satellite campuses on the outskirts of town.

Obama began his Asian tour on a steamy day in Bangkok with a visit to the Wat Pho Royal Monastery. In stocking feet, the president and Secretary of State Hillary Rodham Clinton walked around a golden statue of a sitting Buddha. The complex is a sprawling display of buildings with colorful spires, gardens and waterfalls.

Obama then paid a courtesy call to the ailing, 84-year-old U.S.-born King Bhumibol Adulyadej in his hospital quarters. The king, the longest serving living monarch, was born in Cambridge, Mass., and studied in Europe.

_

Associated Press writer Jim Kuhnhenn contributed to this report.

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Wii U: New console launches in a sea of gadgets

NEW YORK (AP) — In the six years since the last major video game system launched, Apple unveiled the iPhone and the iPad, “Angry Birds” invaded smartphones and Facebook reached a billion users. In the process, scores of video game consoles were left to languish in living rooms alongside dusty VCRs and disc players.

On Sunday, Nintendo Co. is launching the Wii U, a game machine designed to appeal both to the original Wii’s casual audience and the hardcore gamers who skip work to be among the first to play the latest “Call of Duty” release. Just like the Wii U’s predecessor, the Wii, which has sold nearly 100 million units worldwide since 2006, the new console’s intended audience “truly is 5 to 95,” says Reggie Fils-Aime, the president of Nintendo of America, the Japanese company’s U.S. arm.

But the Wii U arrives in a new world. Video game console sales have been falling, largely because it’s been so long since a new system has launched. Most people who wanted an Xbox 360, PlayStation 3 or a Wii already have one. Another reason: People in the broad 5-to-95 age range have shifted their attention to games on Facebook, tablet computers and mobile phones.

U.S. video game sales last month, including hardware, software and accessories, totaled $ 755.5 million, according to the research firm NPD Group. In October 2007, the figure stood at $ 1.1 billion.

The Wii U is likely to do well during the holiday shopping season, analysts believe —so well that shoppers may see shortages. But the surge could peter out in 2013. The Wii U is not expected to be the juggernaut that the Wii was in its heyday, according to research firm IHS iSuppli. The Wii outsold its competitors, the Xbox 360 and the PlayStation 3, in its first four years on sale, logging some 79 million units by the end of 2010. By comparison, IHS expects the Wii U to sell 56.7 million in its first four years.

In the age of a million gadgets and lean wallets, the storied game company faces a new challenge: convincing people that they need a new video game system rather than, say, a new iPad.

The Wii U, which starts at $ 300, isn’t lacking in appeal. It allows for “asymmetrical game play,” meaning two people playing the same game can have entirely different experiences depending on whether they use a new tablet-like controller called the GamePad or the traditional Wii remote. The GamePad can also be used to play games without using a TV set, as you would on a regular tablet. And it serves as a fancy remote controller to navigate a TV-watching feature called TVii, which will be available in December.

Nintendo, known for iconic game characters such as Mario, Donkey Kong and Zelda, is expected to sell the consoles quickly in the weeks leading up to the holidays. After all, it’s been six long years and sons, daughters, brothers and sisters are demanding presents. GameStop Corp., the world’s No. 1 video game retailer, said last week that advance orders sold out and it has nearly 500,000 people on its Wii U waitlist.

Even so, it’s a “very, very crowded space in consumer electronics” this holiday season, notes Ben Bajarin, a principal analyst at Creative Strategies who covers gaming.

Apple‘s duo of iPads, the full-size model and a smaller version called the Mini, will be competing for shoppers’ attention. Not to be outdone, Amazon.com Inc. has launched a trove of Kindle tablets and e-readers in time for the holidays. These range from the Paperwhite, a touch-screen e-reader, to the Kindle Fire HD, which features a color screen and can work with a cellular data plan. Then there are the new laptops and cheaper, thinner “ultrabooks” featuring Microsoft’s new Windows 8 operating system —not to mention smartphones from Apple Inc., Samsung and other manufacturers.

“Nintendo has to be a cut above the noise here,” Bajarin says.

The Wii U is the first major game console to launch in years, but in some ways Nintendo is merely catching up with the HD trend. Sony Corp. and Microsoft Corp. began selling their own powerful, high-definition consoles six and seven years ago, respectively. Both Sony and Microsoft are expected to unveil new game consoles in 2013.

Baird analyst Colin Sebastian thinks the question is not how well the Wii U will do during the holidays, but how it will fare three and six months later.

Gaming has changed significantly in the past six years, especially when it comes to the type of mass-audience experiences that serve as Nintendo‘s bread and butter. Zynga Inc., the online game company behind Facebook games such as “FarmVille” and “Texas HoldEm Poker,” was founded in 2007. The first “Angry Birds” game, that addictive, quirky distraction that has players flinging cartoon birds at structures hiding smug green pigs launched in late 2009. The first iPad, of course, came out in 2010 —three years after the first iPhone.

Fils-Aime acknowledges that Nintendo competes in the broad entertainment landscape, “minute-by-minute,” for consumers’ time.

“That’s true today and that was true 20 years ago,” he says, adding that Nintendo‘s challenge is communicating to people “what is so fun and appealing about the new system.”

Analysts expect Wii U sales to be brisk over the holidays. Nintendo‘s loyal —some would say, fanatical— fan base has been placing advance orders and will likely keep the systems flying off store shelves well into next year. The classic Mario and Zelda games are a huge part of the appeal, since they can’t be played on any gaming system but Nintendo‘s.

Research firm IHS iSuppli estimates that by the end of the year, people will have snapped up 3.5 million Wii U consoles worldwide, compared with 3.1 million Wii units in the same period through the end of 2006.

After the Wii went on sale, shortages persisted for months. Stores were met with long lines of shoppers trying to get their hands on a Wii as late as July 2007, more than seven months after the system’s launch.

Though supply constraints are expected this time around, Fils-Aime says Nintendo will have more hardware available in the Americas than it had for the Wii’s initial months on the market. The company says it will also replenish retailers more frequently than it did six years ago.

An initial sell-out doesn’t mean the Wii U will be successful over the long term, IHS notes, citing its estimate that the Wii U won’t match the Wii’s sales over time.

Bajarin believes it’s going to take “a little bit of time” for the Wii U’s dual-screen gaming concept to sink in with people. If it proves popular, Nintendo could see even more competition at its hands.

“Technologically, it’s not a leap of the imagination to see Apple, Google, Microsoft do something like this,” he says.

____

Follow Barbara Ortutay on Twitter at https://twitter.com/BarbaraOrtutay

Gadgets News Headlines – Yahoo! News

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..

Obama: Historic Myanmar visit underscores democratic progress

BANGKOK (AP) — On the eve of his landmark trip to Myanmar, President Barack Obama tried to assure critics that his visit was not a premature reward for a long-isolated nation still easing its way toward democracy.

"This is not an endorsement of the government," Obama said Sunday in Thailand as he opened a three-country dash through Asia. "This is an acknowledgement that there is a process under way inside that country that even a year and a half, two years ago, nobody foresaw."

Obama was set to become the first U.S. president to visit Myanmar with Air Force One scheduled to touch down in Yangon on Monday morning. Though Obama planned to spend just six hours in the country, the much-anticipated stop came as the result of a remarkable turnaround in the countries' relationship.

The president's Asia tour also marks his formal return to the world stage after months mired in a bruising re-election campaign. For his first postelection trip, he tellingly settled on Asia, a region he has deemed the region as crucial to U.S. prosperity and security.

Aides say Asia will factor heavily in Obama's second term as the U.S. seeks to expand its influence in an attempt to counter China.

China's rise is also at play in Myanmar, which long has aligned itself with Beijing. But some in Myanmar fear that China is taking advantage of its wealth of natural resources, so the country is looking for other partners to help build its nascent economy.

Obama has rewarded Myanmar's rapid adoption of democratic reforms by lifting some economic penalties. The president has appointed a permanent ambassador to the country, also known as Burma, and pledged greater investment if Myanmar continues to progress following a half-century of military rule.

But some human rights groups say Myanmar's government, which continues to hold hundreds of political prisoners and is struggling to contain ethnic violence, hasn't done enough to earn a personal visit from Obama.

Speaking from neighboring Thailand, Obama said Sunday he was under no illusions that Myanmar had done all it needed to do. But he said the U.S. could play a critical role in helping ensure the country doesn't slip backward.

"I'm not somebody who thinks that the United States should stand on the sidelines and not want to get its hands dirty when there's an opportunity for us to encourage the better impulses inside a country," Obama said during a joint press conference Sunday with Thailand's prime minister.

Even as Obama turned his sights on Asia, widening violence in the Middle East competed for his attention.

Obama told reporters Sunday that Israel had the right to defend itself against missile attacks from Gaza. But he urged Israel not to launch a ground assault in Gaza, saying it would put Israeli soldiers, as well as Palestinian citizens, at greater risk and hamper an already vexing peace process.

"If we see a further escalation of the situation in Gaza, the likelihood of us getting back on any kind of peace track that leads to a two-state solution is going to be pushed off way into the future," Obama said.

The ongoing violence is likely to trail Obama as he makes his way from Thailand to Myanmar to Cambodia, his final stop before returning to Washington early Wednesday.

Obama will meet separately in Myanmar with Prime Minister Thein Sein, who has orchestrated much of his country's recent reforms. The president will also meet with longtime Myanmar democracy activist Aung Sun Suu Kyi in the home where she spent years under house arrest.

The president, as he seeks to assuage critics, has trumpeted Suu Kyi's support of his outreach efforts, saying Sunday that she was "very encouraging" of his trip.

The White House says Obama will express his concern for the ongoing ethnic tensions in Myanmar's western Rakhine state, where more than 110,000 people — the vast majority of them Muslims known as Rohingya — have been displaced.

The U.N. has called the Rohingya — who are widely reviled by the Buddhist majority in Myanmar — among the world's most persecuted people.

The White House says Obama will press the matter Monday with Thein Sein, along with demands to free remaining political prisoners as the nation transitions to democracy.

The president will cap his trip to Myanmar with a speech at Rangoon University, the center of the country's struggle for independence against Britain and the launching point for many pro-democracy protests. The former military junta shut the dormitories in the 1990s fearing further unrest and forced most students to attend classes on satellite campuses on the outskirts of town.

Obama began his Asian tour on a steamy day in Bangkok with a visit to the Wat Pho Royal Monastery. In stocking feet, the president and Secretary of State Hillary Rodham Clinton walked around a golden statue of a sitting Buddha. The complex is a sprawling display of buildings with colorful spires, gardens and waterfalls.

Obama then paid a courtesy call to the ailing, 84-year-old U.S.-born King Bhumibol Adulyadej in his hospital quarters. The king, the longest serving living monarch, was born in Cambridge, Mass., and studied in Europe.

_

Associated Press writer Jim Kuhnhenn contributed to this report.

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Pakistan struggles in race to develop armed drones

KARACHI, Pakistan (AP) — Pakistan is secretly racing to develop its own armed drones, frustrated with U.S. refusals to provide the aircraft, but is struggling in its initial tests with a lack of precision munitions and advanced targeting technology.

One of Islamabad's closest allies and Washington's biggest rivals, China, has offered to help by selling Pakistan armed drones it developed. But industry experts say there is still uncertainty about the capabilities of the Chinese aircraft.

The development of unmanned combat aircraft is especially sensitive in Pakistan because of the widespread unpopularity of the hundreds of U.S. drone strikes against Taliban and al-Qaida militants in the country's rugged tribal region bordering Afghanistan.

The Pakistani government denounces the CIA strikes as a violation of the country's sovereignty, though senior civilian and military leaders are known to have supported at least some of the attacks in the past. Pakistani officials also call the strikes unproductive, saying they kill many civilians and fuel anger that helps militants recruit additional fighters — allegations denied by the U.S.

Pakistan has demanded the U.S. provide it with armed drones, claiming it could more effectively carry out attacks against militants. Washington has refused because of the sensitive nature of the technology and doubts that Pakistan would reliably target U.S. enemies. The U.S. has held talks with Pakistan about providing unarmed surveillance drones, but Islamabad already has several types of these aircraft in operation, and the discussions have gone nowhere.

Inaugurating a defense exhibition in the southern city of Karachi last week, Pakistani Prime Minister Raja Pervaiz Ashraf indicated Islamabad would look for help from Beijing in response to U.S. intransigence.

"Pakistan can also benefit from China in defense collaboration, offsetting the undeclared technological apartheid," said Ashraf.

Pakistan has also been working to develop armed drones on its own, said Pakistani military officials and civilians involved in the domestic drone industry, all of whom spoke on condition of anonymity because of the classified nature of the work.

Pakistan first began weapons tests seven or eight months ago with the Falco, an Italian drone used by the Pakistani air force for surveillance that has been modified to carry rockets, said a civilian with knowledge of the secret program. The military is also conducting similar tests with the country's newest drone, the Shahpur, he said. An unarmed version of the Shahpur was unveiled for the first time at the Karachi exhibition.

The weapons tests have been limited to a handful of aircraft, and no strikes have been carried out in combat, said the civilian.

Pakistan lacks laser-guided missiles like the Hellfire used on U.S. Predator and Reaper drones and the advanced targeting system that goes with it, so the military has been using unguided rockets that are much less accurate.

While Hellfire missiles are said to have pinpoint accuracy, the rockets used by Pakistan have a margin of error of about 30 meters (100 feet) at best, and an unexpected gust of wind could take them 300 meters (1,000 feet) from their intended target, said the civilian. Even if Pakistan possessed Hellfires and the guidance system to use them, the missile's weight and drag would be a challenge for the small drones produced by the country.

Pakistan's largest drone, the Shahpur, has a wingspan of about seven meters (22 feet) and can carry 50 kilograms (110 pounds). The U.S. Predator, which can be equipped with two Hellfire missiles, has a wingspan more than twice that and a payload capacity over four times as great.

Pakistani drones also have much more limited range than those produced in the U.S. because they are operated based on "line of sight" using radio waves, rather than military satellites. The Shahpur has a maximum range of 250 kilometers (150 miles), while the Predator can fly over five times that distance.

The British newspaper The Guardian reported Tuesday that Pakistan was working on an armed drone but did not provide details.

The market for drones has exploded in Pakistan and other countries around the world in recent years, as shown by the array of aircraft on display at the defense exhibition in Karachi. Hoping to tap into a worldwide market worth billions of dollars a year, public and private companies wheeled out over a dozen drones that ranged in size from hand-held models meant to be carried in a backpack to larger aircraft like the Shahpur.

All the Pakistani drones on display were advertised as unarmed and meant for surveillance only. One private company, Integrated Dynamics, even promotes its aircraft under the slogan "Drones for Peace." But several models developed by the Chinese government were marketed as capable of carrying precision missiles and bombs.

The Chinese government has offered to sell Pakistan an armed drone it has produced, the CH-3, which can carry two laser-guided missiles or bombs, industry insiders said.

Also being offered to Pakistan is a more advanced drone, the CH-4, which closely resembles a U.S. Reaper and can carry four laser-guided missiles or bombs, according to Li Xiaoli, a representative of the Chinese state-owned company that produces both the CH-3 and CH-4, Aerospace Long-march International Trade Co., Ltd.

Pakistan has yet to purchase any armed Chinese drones because their capabilities have yet to be proven, but is likely to do so in the future, said the civilian with knowledge of the Pakistani military's drone program.

Only a few countries, including the U.S., Britain and Israel, are known to have actually used armed drones in military operations.

"China is a bit of a tough nut to crack as you'd expect," said Huw Williams, a drone expert at Jane's International Defense Review. "They frequently wheel out exciting looking aircraft but are yet to really demonstrate anything earthshattering."

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How new Kindle Fire compares with rivals

Amazon.com Inc. started shipping a larger version of its Kindle Fire HD tablet computer on Thursday. Here’s a look at how it compares with the iPad and other tablets with similar screens.

Amazon.com Inc.‘s Kindle Fire HD 8.9″:

— Price: $ 299 for 16 gigabytes of storage, $ 369 for 32 GB.

— Screen size: 8.9 inches diagonally

— Screen resolution: 1920 by 1200 pixels, at 254 pixels per inch.

— Weight: 1.25 pounds.

— Cameras: Front-facing camera.

— Battery life: 10 hours.

— Operating system: Modified version of Google‘s Android

Pros: Cheap and portable. Convenient access to Amazon store. Dolby audio. Available with access to fast 4G wireless broadband networks, for $ 499 (starts shipping next Tuesday).

Cons: Small selection of third-party applications available from Amazon. No rear camera for taking video and photos.

Apple Inc.‘s iPad:

— Price: Starts at $ 499 for 16 gigabytes of storage, goes up to $ 699 for 64 gigabytes, more for versions with cellular data access. (Apple still sells the older, iPad 2 for $ 399.)

— Screen size: 9.7 inches diagonally

— Screen resolution: 2048 by 1536 pixels, at 264 pixels per inch.

— Weight: 1.44 pounds

— Cameras: 5-megapixel camera on back and a low-resolution camera on front, for videoconferencing

— Battery life: 10 hours.

— Operating system: Apple’s iOS

Pros: Unmatched access to third-party applications, high-quality Apple software and the iTunes store. Widest range of cases and accessories available. Available with access to fast 4G wireless broadband networks, starting at $ 629.

Cons: Data storage cannot be expanded with memory cards.

Google Inc.’s Nexus 10

— Price: $ 399 for 16 gigabytes of storage, $ 499 for 32 GB

— Screen size: 10.1 inches diagonally

— Screen resolution: 2560 by 1600 pixels, at 300 pixels per inch.

— Weight: 1.33 pounds.

— Cameras: 5-megapixel camera on back and a low-resolution camera on front, for videoconferencing

— Battery life: 9 hours for video playback, 7 hours for Web browsing.

— Operating system: Google‘s Android

Pros: Access to a variety of games, utilities and other software for Android devices, though not as extensive as apps available for iPad. Longer, narrower screen better suited to movies. Cheaper than newest full-size iPad.

Cons: Integrates with Google Play store, which is still new and isn’t as robust as Apple or Amazon’s stores. Data storage cannot be expanded with memory cards. No option for cellular wireless broadband.

Samsung Electronic Co.’s Galaxy Tab 2 10.1:

— Price: $ 399 for 16 gigabytes of storage

— Screen size: 10.1 inches diagonally

— Screen resolution: 1280 by 800 pixels, 149 pixels per inch

— Weight: 1.24 pounds

— Cameras: low-resolution front camera, 3-megapixel back.

— Battery life: 11 hours.

— Operating system: Google‘s Android

Pros: Storage is expandable with microSD memory cards. Can act as a universal remote control for an entertainment center. Option for wireless broadband starting in November.

Cons: Selection of third-party applications not as good as iPad’s, but wider than Kindle. Screen resolution lower than iPad’s.

Samsung Electronic Co.’s Galaxy Note 10.1:

— Price: $ 499 for 16 gigabytes of storage, $ 549 for 32 GB

— Screen size: 10.1 inches diagonally

— Screen resolution: 1280 by 800 pixels, 149 pixels per inch

— Weight: 1.3 pounds

— Cameras: low-resolution front camera, 5-megapixel back.

— Battery life: 9 hours.

— Operating system: Google‘s Android

Pros: Comes with a pen, for jotting notes and drawing on the screen. Slightly thinner and lighter than an iPad. Longer, narrower screen better suited to movies. Storage is expandable with microSD memory cards. Can act as a universal remote control for an entertainment center.

Cons: Selection of third-party applications not as good as iPad’s, but wider than Kindle. Screen resolution lower than iPad’s. No option for wireless broadband. Pen sensor slightly shortens battery life.

Barnes & Noble Inc.’s Nook HD+

— Price: $ 269 for 16 gigabytes of storage; $ 299 for 32 GB

— Screen size: 9 inches diagonally

— Screen resolution: 1920 x 1280 pixels, 256 pixels per inch

— Weight: 1.14 pounds

— Cameras: None.

— Battery life: 10 hours of reading, 9 hours of video

— Operating system: Modified version of Google‘s Android

Pros: Cheap and portable. Storage is expandable with microSD memory cards. Easy access to Barnes & Noble book store.

Cons: Selection of third-party applications is small. Barnes & Noble lacks wide range of content. Lacks cameras and option for wireless broadband.

Microsoft Corp.’s Surface:

— Price: $ 499 for 32 gigabytes of storage, $ 100 extra for keyboard cover. $ 699 for 64 GB version, includes keyboard cover.

— Screen size: 10.6 inches diagonally

— Screen resolution: 1366 by 768 pixels, 148 pixels per inch

— Weight: 1.5 pounds.

— Cameras: Front and back cameras

— Battery life: 8 hours.

— Operating system: Microsoft’s Windows RT.

Pros: Storage can be expanded with microSD memory cards. Comes with free Microsoft Office software. Models running full version of Windows 8 coming soon, offering compatibility with programs available for traditional Windows computers.

Cons: Operating system lacks good track record on tablets. Selection of tablet-adapted third-party applications small. No option for wireless broadband.

Gadgets News Headlines – Yahoo! News

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Israel bombards Gaza Strip, shoots down rocket

GAZA CITY, Gaza Strip (AP) — Israel bombarded the Hamas-ruled Gaza Strip with about 300 airstrikes Saturday and shot down a Palestinian rocket fired at Tel Aviv, the military said, widening a blistering assault to include the Hamas prime minister's headquarters, a police compound and a vast network of smuggling tunnels.

The intensified airstrikes came as Egyptian-led attempts to broker a cease-fire and end Israel's four-day-old Gaza offensive gained momentum. The leaders of Hamas and two key allies, Qatar and Turkey, were in Cairo for talks with Egyptian officials, and the Arab League was holding an emergency meeting.

The White House said President Barack Obama was also in touch with the Egyptian and Turkish leaders. The U.S. has solidly backed Israel so far.

Speaking on Air Force One, deputy national security adviser Ben Rhodes said that the White House believes Israel "has the right to defend itself" against attack and that the Israelis will make their own decisions about their "military tactics and operations."

The Israeli attacks, which Gaza officials say left 12 dead, came as Palestinian militants fired more than 100 rockets toward Israel, including two aimed at the commercial and cultural center of Tel Aviv. Rocket attacks on Tel Aviv and Jerusalem this week mark the first time Gaza militants have managed to fire rockets toward the cities, raising the stakes in the confrontation.

The widened scope of targets brings the scale of fighting closer to that of the war the two groups waged four years ago. Hamas was badly bruised during that conflict, but has since restocked its arsenal with more and better weapons, and has been under pressure from smaller, more militant groups to prove its commitment to fighting Israel.

In a psychological boost for the Israelis, a sophisticated Israeli rocket-defense system known as "Iron Dome" knocked down one of the rockets headed toward Tel Aviv, eliciting cheers from relieved residents huddled in fear after air raid sirens sounded in the city.

Associated Press video showed a plume of smoke rising from a rocket-defense battery deployed near the city, followed by a burst of light overhead. The smoke trailed the intercepting missile.

Police said a second rocket also targeted Tel Aviv. It was not clear where it landed or whether it was shot down. No injuries were reported. It was the third straight day the city was targeted.

Israel says the Iron Dome system has shot down some 250 incoming rockets, most of them in southern Israel near Gaza.

Saturday's interception was the first time Iron Dome has been deployed in Tel Aviv. The battery was a new upgraded version that was only activated on Saturday, two months ahead of schedule, officials said.

Israel opened the offensive on Wednesday with a surprising airstrike that killed Hamas' military chief, then attacked dozens of rocket launchers and storage sites. It says the offensive is meant to halt months of rocket fire on southern Israel.

While Israel claims to be inflicting heavy damage on Gaza's Hamas rulers, it has failed to slow the rocket fire. In all, 42 Palestinians, including 13 civilians, have been killed, while three Israeli civilians have died.

Maj. Gen. Tal Russo, Israel's southern commander, said Saturday that Hamas had suffered a tough blow.

"Most of their capabilities have been destroyed," he told reporters. Asked whether Israel is ready to send ground troops into Gaza, he said: "Absolutely."

Israel has authorized the call-up of as many as 75,000 reservists ahead of a possible ground operation. Dozens of armored vehicles have massed along the border with Gaza in recent days.

Israeli officials say they have not yet decided whether to send in ground troops, a decision that would almost certainly lead to heavy casualties on both sides.

In Saturday's fighting, Israeli aircraft pounded militants' weapons storage facilities and underground rocket launching sites, and went after rocket squads more aggressively.

Militants, undaunted, have unleashed some 500 rockets against the Jewish state.

Hamas claims that Israeli intelligence is based on a network of collaborators in Gaza. Officials said two Palestinians have been executed by Hamas' military wing for allegedly providing Israel with sensitive information. One man was shot twice in the head. Another body was tossed into a garbage bin with a gunshot wound to the head.

The violence has threatened the Mideast with a new war. At the same time, revolts against entrenched regional regimes have opened up new possibilities for Hamas. Islamists across the Mideast have been strengthened, bringing newfound recognition to Hamas, which had previously been shunned by the international community because of its refusal to recognize Israel and renounce violence.

A high-level Tunisian delegation, led by Foreign Minister Rafik Abdessalem, drove that point home with a visit to Gaza on Saturday. The foreign minister's first stop was the still-smoldering ruins of the three-story office building of Gaza's prime minister, Ismail Haniyeh of Hamas.

"Israel has to understand that there is an international law and it has to respect the international law to stop the aggression against the Palestinian people," Abdessalem told the AP during a tour of Gaza's main hospital. He said his country was doing whatever it can to promote a cease-fire, but did not elaborate.

It was the first official Tunisian visit since Hamas's violent 2007 takeover of the territory. The West Bank is governed by Palestinian President Mahmoud Abbas. Egypt's prime minister visited Gaza on Friday and a Moroccan delegation was due on Sunday, following a landmark visit by Qatar's leader last month.

Israel had been incrementally expanding its operation beyond military targets but before dawn on Saturday it ramped that up dramatically, hitting Hamas symbols of power.

Israeli defense officials, speaking on condition of anonymity to discuss confidential decisions, said military chief Lt. Gen. Benny Gantz personally ordered the scope of the airstrikes to be increased.

Haniyeh's three-story office building was flattened by an airstrike that blew out windows in neighboring homes. He was not inside the building at the time.

Another airstrike brought down the three-story home of a Hamas commander in the Jebaliya refugee camp near Gaza City, critically wounding him and injuring other residents of the building, medics said.

Missiles smashed into two small security facilities and the massive Hamas police headquarters in Gaza City, setting off a huge blaze that engulfed nearby houses and civilian cars parked outside, the Interior Ministry reported. No one was inside the buildings.

The Interior Ministry said a government compound was also hit while devout Muslims streamed to the area for early morning prayers, although no casualties were reported.

Air attacks knocked out five electricity transformers, cutting off power to more than 400,000 people in southern Gaza, according to the Gaza electricity distribution company. People switched on backup generators for limited electrical supplies.

In southern Gaza, aircraft went after underground tunnels militants use to smuggle in weapons and other contraband from Egypt, residents reported. A huge explosion in the area sent buildings shuddering in the Egyptian city of El-Arish, 45 kilometers (30 miles) away, an Associated Press correspondent there reported.

The Israeli military said more than 950 targets have been struck since the operation began.

On Saturday, more than 120 rockets slammed into Israel, causing damage to houses. About 10 Israelis were injured lightly, among dozens of others wounded since the start of the operation.

Despite the violence, Egyptian-led diplomacy was underway to bring an end to the fighting.

Egyptian President Mohammed Morsi was meeting the leaders of Turkey and Qatar Saturday as well as Hamas leader Khaled Meshal to discuss details of a proposed cease-fire.

The Arab League also met Saturday to consider sending its chief Nabil Elaraby and a team of foreign ministers to Gaza in the coming two days to assess the situation and respond to humanitarian needs there, according to a draft memorandum obtained by the AP.

Turkish Prime Minister Recep Tayyip Erdogan told reporters Saturday that during discussions with Obama and Russian President Vladimir Putin late Friday, he suggested that Turkey, Egypt, the United States and Russia help broker a simultaneous cease-fire between Israel and Hamas.

"It would be good if we could work on it rapidly to solve the matter within 24 hours, because the death toll is mounting," he said.

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Goldenberg reported from Jerusalem. Associated Press writers Karin Laub in Gaza City, Matthew Daly in Washington and Aya Batrawy in Cairo contributed reporting.

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